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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1603171Generated: November 2, 2026

4-Hydroxybenzaldehyde → Licochalcone A

https://huagongshe.com/reaction/1603171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxybenzaldehydeHCID 126—
Reactant2-Methoxy-4-[(3-methyl-2-buten-1-yl)oxy]benzaldehydeHCID 11085319—
ReactantHCID 12153345HCID 12153345—
ProductLicochalcone AHCID 5318998—

Reaction Steps

The Claisen rearrangement of 2-methoxy-4-(3-methylbut-2-enyloxy)benzaldehyde and the Claisen condensation of the resulting 2-methoxy-4hydroxy-5-(1,1-dimethyl-prop2-enyl)benzaldehyde with 4-hydroxybenzaldehyde to give licochalcone A was performed according to the Chinese procedure:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05985935
Source datasetuspto-grants-1999_11
ORD IDord-8dfb719f6072459a8aa944c86404b672
Source noteuspto-grants-1999_11