HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → Ethyl 3-(dibutylamino)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Dibutylamine | HCID 8148 | — |
| Reactant | Ethyl 3-bromopropionate | HCID 68320 | — |
| Solvent | Pentane | HCID 8003 | — |
| Product | Ethyl 3-(dibutylamino)propanoate | HCID 88373 | — |
Reaction Steps
Ethyl 3-bromopropionate (18.0 g; 0.10 mol) was added carefully to di-n-butylamine (25.8 g; 0.20 mol), followed by stirring for 2 hours. Then diethyl ether (200 ml) and pentane (200 ml) were added. The precipitate was filtered off, the filtrate was evaporated and the residue was distilled at sub-atmospheric pressure. The yield was 7.0 g (31%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05986029 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-a6d6605e9cbc42a8a1f05a78bf435d18 |
| Source note | uspto-grants-1999_11 |