HCID 15289121, compound → HCID 15289122, compound

HRID 1603219Notes

Reaction equation

HRID 1603219 reaction equation
[NH2:1][CH2:2][C:3]12[CH2:13][CH2:12][CH:9]([CH:10]=[CH:11]1)[CH:8]1[CH:4]2[CH2:5][N:6](CC2C=CC=CC=2)[CH2:7]1>[Pd]>[NH2:1][CH2:2][C:3]12[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13]1)[CH:8]1[CH:4]2[CH2:5][NH:6][CH2:7]1

Participants

3

Reactant 1

HCID 15289121HCID 15289121, compound

Product 1

HCID 15289122HCID 15289122, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

7.4 g (27.5 mmol) of 1-aminomethyl-4-benzyl-4-azatricyclo[5.2.2.02,6 ]undec-8-ene are hydrogenated in 100 ml of tetahydrofuran using 1.5 g of palladium/active charcoal at 100° C./100 bar. The catalyst is filtered off with suction and the residue is distilled.

Workup

  1. customat 100° C.
  2. filtrationThe catalyst is filtered off with suction
  3. distillationthe residue is distilled

Sources & evidence

ORD record
ord-b391e213eee14f3da67ebbffe4e57753
Source dataset
uspto-grants-1999_11
Patent number
US05986105

Reaction notes

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