Tetrahydrofuran → HCID 67580135, compound

Participants

Reaction Steps

A solution of 6.0 g (0.03 mole) of iminostilbene in 250 mL of chloroform was added to a solution of 10 g (0.09 mole) of sodium carbonate in 100 mL of water and the mixture was stirred rapidly. To this rapidly stirring solution 6.2 g (0.03 mole) of bromoacetyl bromide was added dropwise through an additional funnel, at which time thin layer chromatography analysis using 2:1 THF:hexane indicated the reaction was incomplete. An additional 1.0 g (0.005 mole) of bromoacetyl bromide was added. Thin layer chromatography indicated that the starting material had been totally consumed. The chloroform layer was separated, dried over Na2SO4 and concentrated to yield 11.0 g of N-bromoacetyliminostilbene (38) as a light yellow oil. This material was used in the following reaction.

Provenance & Evidence