HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimedone → HCID 178462307, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimedone | HCID 31358 | — |
| Reactant | allyl (1S,5R,6S)-2-(hydroxymethyl)-6-[1(R)-allyloxycarbonyloxy-ethyl]-1-methylcarbapen-2-em-3-carboxylate | HCID 11046746 | — |
| Reactant | HCID 19605200 | HCID 19605200 | — |
| Product | HCID 178462307 | HCID 178462307 | 5.4% |
Reaction Steps
The same procedure as in Example 1 was repeated except that dimedone was used as a trapping agent in a deprotective reaction, and 145 mg of allyl (1S,5R,6S)-6-[(1R)-1-allyloxycarbonyloxyethyl]-2-hydroxymethyl-1-methyl-1-carbapen-2-em-3-carboxylate and 340 mg of 3-[N-(2-allyloxycarbonylaminoethyl)carbamoyl]imidazo[5,1-b]thiazole were used, thereby obtaining 9.3 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05990101 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-bf9d9c781db44d579675a2fa6b774918 |
| Source note | uspto-grants-1999_11 |