Ethyl Acetate → HCID 19605507, compound

Participants

Reaction Steps

0.15 g (0.00042 mol) of 2-bromo-6-methyl-4-(4-nitrobenzenesulphonyl)-pyridine was dissolved in 10 ml of methanol, treated with 0.18 g of iron powder and a solution of 0.18 g of NH4Cl in 5 ml of water and heated at reflux for 1 hr. Thereafter, the reaction mixture was poured into a mixture of ethyl acetate and water, suction filtered and the organic phase was extracted with water and sat. sodium chloride solution and dried over MgSO4. After removal of the solvent the residue was dried in a high vacuum. There was obtained 0.134 g (98%) of 4-(2-bromo-6-methylpyridine-4-sulphonyl)-phenylamine as yellowish crystals; m.p.: 189-191° C.

Provenance & Evidence