Sodium hydride → HCID 19605405, compound

Participants

Reaction Steps

Treatment of 4-benzylthio-2-oxo-azetidine (1.35 g) in THF with NaH (0.18 g) followed by 9-phenylnonyltriflate (2.8 g) gave the title compound as a colourless oil, 1.9 g, 68% yield. 1H NMR δ (CDCl3) 1.2-1.7 (14H, m, 7×CH2), 2.60 (2H, t, J=8 Hz, CH2Ar), 2.8, 3.2 (each 2H, m, H3 +NCH2), 3.76 (2H, s, SCH2), 4.59 (1H, m, H4), 7.15-7.35 (10H, m, Ph--H)

Provenance & Evidence