反应详情

6-Phenylhexanoic acid (2.5 g, 13 mmol) was treated with thionyl chloride (3.0 ml, 41.1 mmol) and stirred under reflux for 3 h. The mixture was evaporated under reduced pressure to remove thionyl chloride and then distilled at 92-95° C./0.1 mbar to give the product as a colourless oil (2.57 g, 94%).

1. temperatureunder reflux for 3 h
2. customThe mixture was evaporated under reduced pressure
3. customto remove thionyl chloride
4. distillationdistilled at 92-95° C./0.1 mbar