Benzylmaleimide → HCID 15289129, compound

HRID 1603701Notes

Reaction equation

HRID 1603701 reaction equation
[CH2:1]([N:8]1[C:12](=[O:13])[CH:11]=[CH:10][C:9]1=[O:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C12(C(OCC)=O)CC(C=C1)[CH:20]1[CH:16]2[CH:17]=[C:18]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH2:19]1>O1CCOCC1>[CH2:28]([O:27][C:25]([C:18]12[CH2:19][CH:20]([CH:16]=[CH:17]1)[CH:11]1[CH:10]2[C:9](=[O:14])[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[C:12]1=[O:13])=[O:26])[CH3:29]

Participants

4

Reactant 2

HCID 74204BenzylmaleimideHCID 15289128HCID 15289128, compound

Product 1

HCID 15289129HCID 15289129, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

32.8 g (0.17 mol) of N-benzylmaleimide are heated under reflux with 24.2 g (0.17 mol) of diethyl tricyclo[5.2.1.02,6 ]deca-3,8-diene-1,4-dicarboxylate in 200 ml of 1,4-dioxane overnight. The mixture is concentrated, the residue is taken up in 80 ml of isopropanol and the product is allowed to crystallize out.

Workup

  1. concentrationThe mixture is concentrated
  2. customto crystallize out

Sources & evidence

ORD record
ord-7b3c42a7c377418aa368fcdf8b72a916
Source dataset
uspto-grants-1999_11
Patent number
US05990122

Reaction notes

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