HCID 54474771, compound → HCID 19606231, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 38 g of α-{2-[1-(α,α,α-trifluoro-4-tolyl)-2-imidazolidinon-3-yl]ethoxy]toluene in 400 ml of 1,4-dioxane, 15 g of 7.5% palladium carbon were added, followed by stirring under a hydrogen gas stream at 50° C. and 30 atm for 15 hours. After the reaction mixture was filtered, the filtrate was concentrated under reduced pressure. Resulting crystals were collected by filtration and then washed with ether, whereby 16.4 g of the title compound were obtained (yield: 58%).

Provenance & Evidence