5-Methoxy-6-(trifluoromethyl)indoline → HCID 10791286, compound

HRID 1603791Notes

Reaction equation

HRID 1603791 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH:14][C:15](=[O:23])OC2C=CC=CC=2)[CH:5]=[C:6]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[CH:7]=1.[CH3:24][O:25][C:26]1[CH:27]=[C:28]2[C:32](=[CH:33][C:34]=1[C:35]([F:38])([F:37])[F:36])[NH:31][CH2:30][CH2:29]2>>[Br:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[CH:5]=[C:4]([NH:14][C:15]([N:31]2[C:32]3[C:28](=[CH:27][C:26]([O:25][CH3:24])=[C:34]([C:35]([F:37])([F:38])[F:36])[CH:33]=3)[CH2:29][CH2:30]2)=[O:23])[CH:3]=1

Participants

3

Reactant 2

HCID 112067135-Methoxy-6-(trifluoromethyl)indolineHCID 18005087HCID 18005087, compound

Product 1

HCID 10791286HCID 10791286, compound

Procedure

The title compound was prepared from phenyl N-[3-bromo-5-(pyrid-3-yl)phenyl]carbamate (D21) and 5-methoxy-6-trifluoromethylindoline (D11) using the method of Example 28.

Sources & evidence

ORD record
ord-24ca4c98bdee469eb23809a2e7b3abdb
Source dataset
uspto-grants-1999_11
Patent number
US05990133

Reaction notes

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