HRID160380

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID923

Sodium ion

Na+

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID166653

Hydride

H-

HCID238253

3,3-diphenylpyrrolidin-2-one

C16H15NO

HCID2794629

5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole

C12H9BrF3NS

PRODUCTS

生成物

结构：Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CN1CCC(c2ccccc2)(c2ccccc2)C1=O

HCID67357712

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-289ca6bcc20b49eba9d84e17085e4795
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (9/10)

反应 SMILES

[Br:21][CH2:22][c:23]1[c:24]([CH3:38])[n:25][c:26](-[c:28]2[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]2)[s:27]1.[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[H-:19].[Na+:20].[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[C:8](=[O:12])[NH:9][CH2:10][CH2:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[C:8](=[O:12])[N:9]([CH2:22][c:23]3[c:24]([CH3:38])[n:25][c:26](-[c:28]4[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]4)[s:27]3)[CH2:10][CH2:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1