HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-2-hydroxyacetophenone → N-(3-acetyl-2-hydroxyphenyl)-2-(benzyloxymethyl)benzofuran-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-2-hydroxyacetophenone | HCID 459294 | — |
| Reactant | 2-(Benzyloxymethyl)benzofuran-5-carboxylic acid | HCID 19606321 | — |
| Product | N-(3-acetyl-2-hydroxyphenyl)-2-(benzyloxymethyl)benzofuran-5-carboxamide | HCID 19606326 | 98% |
Reaction Steps
Following the process described in example 1 (point K), starting from 2-(benzyloxymethyl)benzofuran-5-carboxylic acid and 3-amino-2-hydroxyacetophenone, the title compound was prepared as a yellowish solid with melting point 92-94° C., which was purified by chromatography through a silica gel column (98% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05990142 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-491a49e5eb7742d1ac41bd514aea0e67 |
| Source note | uspto-grants-1999_11 |