HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-(Chloromethyl)-4-(4-phenylbutoxy)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(4-Phenylbutoxy)benzyl alcohol | HCID 54034605 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(Chloromethyl)-4-(4-phenylbutoxy)benzene | HCID 15115532 | — |
Reaction Steps
A solution of 4-(4-phenylbutoxy)benzyl alcohol (556 mg, 2.17 mmol) in chloroform (10 ml) was added with thionyl chloride (0.288 ml) and left under stirring at room temperature for 24 h, then evaporated to dryness under reduced pressure to obtain 595 mg of the title compound (quantitative yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05990142 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-8121dce99eb24a3d85d878cbc6d419a9 |
| Source note | uspto-grants-1999_11 |