HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Phenylbutoxy)-2-fluorostyrene → 3'-[(E)-2-[4-(4-Phenylbutoxy)-2-fluorophenyl]ethen-1-yl]-2'-hydroxyacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Phenylbutoxy)-2-fluorostyrene | HCID 19606296 | — |
| Reactant | 1-(2-Hydroxy-3-iodophenyl)ethan-1-one | HCID 19606310 | — |
| Product | 3'-[(E)-2-[4-(4-Phenylbutoxy)-2-fluorophenyl]ethen-1-yl]-2'-hydroxyacetophenone | HCID 19606370 | 67% |
Reaction Steps
Following the process described in example 20 (point D), starting from 4-(4-phenylbutoxy)-2-fluorostyrene and 2'-hydroxy-3'-iodoacetophenone, the title compound was prepared, which was purified by flash chromatography through a column, eluting with petroleum ether:ethyl acetate, 95:5 (67% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05990142 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-c13965d2b6a544c38c7e384d32dba8e4 |
| Source note | uspto-grants-1999_11 |