HCID 18692238, compound → HCID 18692265, compound

Participants

Reaction Steps

Into a reducing device equipped with a thermometer, a reflux condenser and an agitator were charged 36.5 g of 1,4-bis(3-nitro-5-trifluoromethylphenoxy)benzene (0.0747 mol), 250 mL of N,N-dimethylformamide and 1.8 g of Pd-alumina, and the mixture was reacted at 50° C. for 6 hours in an atmosphere of hydrogen. At the end of the reaction, the catalyst was filtered out, the filtrate was condensed under a reduced pressure to give 1,4-bis(3-amino-5-trifluoromethylphenoxy)benzene as white crystals; Melting point: 157.4 to 159.0° C., Yield: 29.6 g (92.5%).

Provenance & Evidence