Tributylstannane → HCID 13168697, compound

Participants

Reaction Steps

Scheme D shows a method of preparing an aldehyde which may be used in Scheme A. 1-Methoxy-1E-buten-3-yne is reacted with tributylstannane in the presence of catylytic 2,2'-azobisisobutyronitrile (AIBN) to give tributyl(4-methoxy-1E,3E-butadienyl)stannane which is then reacted with butyllithium followed by coupling with an appropriate aldehyde (XVIII). The alcohol-formed is reacted with toluene sulfonic acid (TSOH) to give the desired aldehyde (V).

Provenance & Evidence