3,5-Dinitrobenzyl alcohol → (3,5-Diaminophenyl)methanol

HRID 1604145Notes

Reaction equation

HRID 1604145 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([N+:12]([O-])=O)[CH:11]=1)[CH2:7][OH:8])([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([NH2:12])[CH:11]=1)[CH2:7][OH:8]

Participants

4

Reactant 1

HCID 1169783,5-Dinitrobenzyl alcohol

Product 1

HCID 586680(3,5-Diaminophenyl)methanol

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 3,5-dinitrobenzylalcohol (2.20 g, 11.1 mmol) in methanol (90 ml) and a Pd/C catalyst (10%, 100 mg) was hydrogenated in a Parr apparatus at 60 psi. The solution was filtered and the solvent was removed by evaporation. The crude product was used without purification in the next step.

Workup

  1. filtrationThe solution was filtered
  2. customthe solvent was removed by evaporation
  3. customThe crude product was used without purification in the next step

Sources & evidence

ORD record
ord-662f30fa959041deb68b94c744dc32e7
Source dataset
uspto-grants-1999_11
Patent number
US05993780

Reaction notes

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