1-Acetoxy-2-bromoethane → HCID 53872218, compound

HRID 1604182Notes

Reaction equation

HRID 1604182 reaction equation
[C:1]([O:4][CH2:5][C:6]([NH:8][C:9]1[C:10]([I:41])=[C:11]([CH2:36][O:37][C:38](=[O:40])[CH3:39])[C:12]([I:35])=[C:13]([C:33]=1[I:34])[C:14]([NH:16][CH:17]([CH:23]([O:29][C:30](=[O:32])[CH3:31])[CH2:24][O:25][C:26](=[O:28])[CH3:27])[CH2:18][O:19][C:20](=[O:22])[CH3:21])=[O:15])=[O:7])(=[O:3])[CH3:2].[C:42]([O:45][CH2:46][CH2:47]Br)(=[O:44])[CH3:43]>>[C:42]([O:45][CH2:46][CH2:47][N:8]([C:9]1[C:10]([I:41])=[C:11]([CH2:36][O:37][C:38](=[O:40])[CH3:39])[C:12]([I:35])=[C:13]([C:33]=1[I:34])[C:14]([NH:16][CH:17]([CH:23]([O:29][C:30](=[O:32])[CH3:31])[CH2:24][O:25][C:26](=[O:28])[CH3:27])[CH2:18][O:19][C:20](=[O:22])[CH3:21])=[O:15])[C:6](=[O:7])[CH2:5][O:4][C:1](=[O:3])[CH3:2])(=[O:44])[CH3:43]

Participants

3

Reactant 2

HCID 135641-Acetoxy-2-bromoethaneHCID 53891430HCID 53891430, compound

Product 1

HCID 53872218HCID 53872218, compound

Procedure

5-(Acetoxyacetamido)-3-acetoxymethyl-N-(1,3,4-triacetoxybut-2-yl)-2,4,6-triiodobenzamide was alkylated with 2-bromoethyl acetate according to the procedure in Example 25a. Yield of crude product=97%.

Sources & evidence

ORD record
ord-f023d315bf2a429bb6eb0ca004b01475
Source dataset
uspto-grants-1999_11
Patent number
US05993780

Reaction notes

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