HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → N,N-Diethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | N,N-Diethyl-1-naphthamide | HCID 229388 | — |
| Product | N,N-Diethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide | HCID 15828028 | 71% |
Reaction Steps
N,N-Diethyl-1-naphthalenecarboxamide was reacted with 2 eq TMSCl according to General Method A. The resulting reaction mixture was worked up in the usual manner, then purified by chromatography with 20% ethyl acetate/80% hexanes to afford 2.1 g of the desired compound as a clear oil, a 71% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05994270 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-3e590ffdfe7c427881eabbc3eee42cca |
| Source note | uspto-grants-1999_11 |