HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → N-Ethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | N-ethyl-1-naphthalenecarboxamide | HCID 4088726 | — |
| Product | N-Ethyl-2-(trimethylsilyl)-1-naphthalenecarboxamide | HCID 19602329 | 58% |
Reaction Steps
N-Ethyl-1-naphthalenecarboxamide was reacted with 2 eq TMSCl according to General Method C. The resulting reaction mixture was worked up in the usual manner, then purified by recrystallization from cold ethyl acetate/hexanes to afford 1.6 g of desired compound as a white solid, a 58% yield. m.p. 141-143° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05994270 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-632443465f9a46ed8b8d291916272c7f |
| Source note | uspto-grants-1999_11 |