反应详情

温度

0 °C

To 11.3 g KOH (176 mmol) in 100 mL ethanol at 0° C. was added in small portions 22.2 g of 2,3-dibromo-2,3-dihydrobenzofuran, and the resulting reaction mixture was stirred at 0° C. for an additional 3 h. Most of the solvent was then removed in vacuo. Water and ether were added to the residue. The aq layer was separated and extracted with ether. The combined ether layers were washed with water and brine, dried (MgSO4), and concentrated to give 17 g of 3-bromobenzofuran.

1. customthe resulting reaction mixture
2. customMost of the solvent was then removed in vacuo
3. additionWater and ether were added to the residue
4. customThe aq layer was separated
5. extractionextracted with ether
6. washThe combined ether layers were washed with water and brine
7. dry with materialdried (MgSO4)
8. concentrationconcentrated