HCID 9866247, compound → HCID 131721470, compound

Participants

Reaction Steps

A mixture of 7-bromo-3-carbo-ter-butoxy-2-methyl-2,3-dihydro-1H-phenothiazin-4[10H]-one (4l R=Br, 3.09 g, 13.7 mmole) in DMSO (10 mL) is placed in a preheated heating mantle. The reaction mixture is stirred and refluxed for 3 h. Upon cooling, the reaction mixture forms a solid. The crystals are filtered and the remaining mother liquid is poured into cold water, whereupon further precipitation occurs. Each precipitate is separately recrystallized twice from MeOH and proves to be identical. An analytical sample of 4m, (R=Br), mp 250° (dec.) occurs as light orange crystals, 2.67 g (63.2%).

Provenance & Evidence