6-Chloro-3-pyridinecarbonitrile → HCID 22622542, compound

HRID 1604391Notes

Reaction equation

HRID 1604391 reaction equation
[CH2:1]([NH:3][CH2:4][C:5]1[CH:10]=[C:9]([Br:11])[CH:8]=[CH:7][C:6]=1[O:12][CH2:13][CH:14]1[CH2:16][CH2:15]1)[CH3:2].Cl[C:18]1[CH:23]=[CH:22][C:21]([C:24]#[N:25])=[CH:20][N:19]=1>>[Br:11][C:9]1[CH:8]=[CH:7][C:6]([O:12][CH2:13][CH:14]2[CH2:15][CH2:16]2)=[C:5]([CH:10]=1)[CH2:4][N:3]([C:18]1[CH:23]=[CH:22][C:21]([C:24]#[N:25])=[CH:20][N:19]=1)[CH2:1][CH3:2]

Participants

3

Reactant 2

HCID 51520946-Chloro-3-pyridinecarbonitrileHCID 22622484HCID 22622484, compound

Product 1

HCID 22622542HCID 22622542, compound

Procedure

The title compound was prepared by reacting N-ethyl-5-bromo-2-cyclopropylmethoxybenzylamine (reference example 13) and 2-chloro-5-cyanopyridine using a similar method to that of reference example 18.

Sources & evidence

ORD record
ord-a456eb099a3d4448908d0dd40b1aaba4
Source dataset
uspto-grants-1999_11
Patent number
US05994353

Reaction notes

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