Ethyl 4-(2-(10-(Isopropylthio)decanoylamino)phenylthio)butyrate → 4-(2-(11-Carboxyundecanoylamino)phenylthio)butyric acid

Participants

Role	Name	HCID	Charge
Reactant	Ethyl 4-(2-(10-(Isopropylthio)decanoylamino)phenylthio)butyrate	HCID 18796066	—
Reactant	Ethyl 4-[(2-amino-3-methylphenyl)sulfanyl]butanoate	HCID 19603177	—
Reactant	Dodecanedioic acid, monomethyl ester	HCID 22672980	—
Product	4-(2-(11-Carboxyundecanoylamino)phenylthio)butyric acid	HCID 18795722	—

Reaction Steps

When amine (11) is acylated with acid chloride (7) as per procedure Step (E), and the resultant diester (ethyl 4-(2-(11-carbomethoxyundecanoylamino)phenylthio)butyrate 12 is hydrolyzed in Step I as per procedure (F), the title compound, 13 m.p. 113.5-115° C. is obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05994362
Source dataset	uspto-grants-1999_11
ORD ID	ord-b20c93ebadbb456582ee5bbf98df0e50
Source note	uspto-grants-1999_11