Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lipoic acid | HCID 6112 | — |
| Solvent | Diisopropyl Ether | HCID 7914 | — |
| Product | alpha Lipoic acid | HCID 864 | 362.5% |
Reaction Steps
A solution which contained 4.0 g R-(+)-thioctic acid and 16.0 g S-(-)-thioctic acid in 80 ml diisopropyl ether was cooled off from 35 to 40° C. down to -5 to -10° C., filtered and dried. 14.5 g thioctic acid were obtained in the novel modification as first crystallizate. The S-(-)thioctic acid content was 75.8% with a melting range of 50 to 56° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05994393 |
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| Source dataset | uspto-grants-1999_11 |
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| ORD ID | ord-23595304fa8748e1b80d1865b6710d51 |
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| Source note | uspto-grants-1999_11 |
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