4-Methylbenzoyl Chloride → HCID 18627818, compound

HRID 1604479Notes

Reaction equation

HRID 1604479 reaction equation
[NH2:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[C:11]1([CH3:20])[CH:16]=[CH:15][C:14]([C:17](Cl)=[O:18])=[CH:13][CH:12]=1>>[C:11]1([CH3:20])[CH:16]=[CH:15][C:14]([C:17]([NH:1][CH:2]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH2:4][CH2:3]2)=[O:18])=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 134054-Methylbenzoyl ChlorideHCID 123445(+-)-1-Aminoindan

Product 1

HCID 18627818HCID 18627818, compound

Procedure

The title compound was prepared from (rac)-1-aminoindan (5.0 g, 37.6 mmole) and p-toluoyl chloride (5.2 g, 33.8 mmole) as in Ex. 52; 4.8 g (19.1 mmole, 57%), mp: 140° C.

Sources & evidence

ORD record
ord-92bf36b0e2734fc598c92b62ed8d2e32
Source dataset
uspto-grants-1999_11
Patent number
US05994408

Reaction notes

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