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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1604528Generated: October 25, 2026

4-Acetylaminocinnamic acid → 3-(4-Acetamidophenyl)propanoic acid

https://huagongshe.com/reaction/1604528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Acetylaminocinnamic acidHCID 251522—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product3-(4-Acetamidophenyl)propanoic acidHCID 23291185.4%

Reaction Conditions

Temperature25 °C

Reaction Steps

4-Acetamidocinnamic acid (80 mg) was suspended in methanol (5 ml) and 10% palladium on carbon (15 mg) was added thereto. The mixture was stirred under hydrogen atmosphere at 25° C. for 3 hours. Catalyst was removed and the solution was concentrated to give 3-(4-acetamidophenyl)propionic acid (69 mg) as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05994368
Source datasetuspto-grants-1999_11
ORD IDord-ddc6aa0820134d3b932a03957f2c437b
Source noteuspto-grants-1999_11