HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Ethyl 3-(2-methoxyanilino)-2-methyl-2-butenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Ethyl 2-methylacetoacetate | HCID 701 | — |
| Reactant | 2-Methoxyaniline | HCID 7000 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Ethyl 3-(2-methoxyanilino)-2-methyl-2-butenoate | HCID 67566028 | — |
Reaction Steps
A mixture of 2-methoxyaniline (10 g), acetic acid (1 ml) and ethyl 2-acetylpropionate (12.3 g) in benzene (30 ml) was refluxed for 24 hours, and then the solvent was removed to give crude ethyl 3-(2-methoxyanilino)-2-methyl-2-butenoate, which was used as a starting compound at the following example without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05994368 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-074ae69a55d343abad7b707f2f790133 |
| Source note | uspto-grants-1999_11 |