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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1604574Generated: October 31, 2026

HCID 19603401, compound → HCID 19603330, compound

https://huagongshe.com/reaction/1604574

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19603401HCID 19603401—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 19603330HCID 1960333055.8%

Reaction Steps

A mixture of 8-benzyloxy-4-ethoxycarbonylmethoxy-2-methylquinoline (1.30 g) and palladium on carbon (130 mg) in a mixture of ethanol (8 ml) and dioxane (7 ml) was stirred for 3 hours at ambient temperature under hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated in vacuo to give 4-ethoxycarbonylmethoxy-8-hydroxy-2-methylquinoline (539 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05994368
Source datasetuspto-grants-1999_11
ORD IDord-4a5db98fffaf43aab6760c5c1da87430
Source noteuspto-grants-1999_11