Cyanamide → HCID 12272862, compound

HRID 1604929Notes

Reaction equation

HRID 1604929 reaction equation
Cl.[CH3:2][CH:3]([C:8]#[N:9])[C:4](=[NH:7])[O:5][CH3:6].[N:10]#[C:11]N>C1C=CC=CC=1>[C:11]([N:7]=[C:4]([O:5][CH3:6])[CH:3]([C:8]#[N:9])[CH3:2])#[N:10]

Participants

4

Reactant 2

HCID 9864CyanamideHCID 21548201HCID 21548201, compound

Product 1

HCID 12272862HCID 12272862, compoundYield 86.8%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

2.97 g of methyl α-methylcyanoacetimidate hydrochloride and 1.26 g of cyanamide were suspended in 30 ml of benzene and made to react for 5 hours at 25°C. Then, ammonium chlordie precipitate was filtered off and then the filtrate was concentrated to dryness in vacuo and 2.38 g of methyl N-cyano-α-methycyanoacetimidate was obtained (yield 86.8%) mp 68.5°C. Analysis calculated for C6H7N3O (%) C 52.54, H 5.15, N 30.64, found C 52.57, H 5.14, N 30.62.

Workup

  1. customto react for 5 hours at 25°C
  2. filtrationThen, ammonium chlordie precipitate was filtered off
  3. concentrationthe filtrate was concentrated to dryness in vacuo

Sources & evidence

ORD record
ord-57e4eeafc8d44d89aa51943165e9e5dc
Source dataset
uspto-grants-1976_04
Patent number
US03948915

Reaction notes

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