Cyanamide → HCID 12272863, compound

HRID 1604930Notes

Reaction equation

HRID 1604930 reaction equation
Cl.[C:2]1([CH:8]([C:13]#[N:14])[C:9](=[NH:12])[O:10][CH3:11])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:15]#[C:16]N>C1C=CC=CC=1>[C:16]([N:12]=[C:9]([O:10][CH3:11])[CH:8]([C:13]#[N:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)#[N:15]

Participants

4

Reactant 2

HCID 9864CyanamideHCID 21548199HCID 21548199, compound

Product 1

HCID 12272863HCID 12272863, compoundYield 76.9%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4.21 g of methyl α-phenylcyanoacetimidate hydrochloride and 1.26 g of cyanamide were mixed at room temperature and the mixture was made to react for 5 hours. Then, 50 ml of benzene was added to the reaciton mixture to extract the resulting product. The extracted solution was concentrated to dryness in vacuo and 3.06 g of methyl N-cyano-α-phenylcyanoacetimidate was obtained (yield 76.8%).

Workup

  1. customto react for 5 hours
  2. extractionto extract the resulting product
  3. concentrationThe extracted solution was concentrated to dryness in vacuo

Sources & evidence

ORD record
ord-e5b14c65e3834a3e8efb6d9353c6cc2e
Source dataset
uspto-grants-1976_04
Patent number
US03948915

Reaction notes

Loading…