Cyanamide → HCID 12272861, compound

HRID 1604933Notes

Reaction equation

HRID 1604933 reaction equation
Cl.[C:2]([CH2:4][C:5](=[NH:8])[O:6][CH3:7])#[N:3].[N:9]#[C:10]N>C1C=CC=CC=1>[C:10]([N:8]=[C:5]([O:6][CH3:7])[CH2:4][C:2]#[N:3])#[N:9]

Participants

4

Reactant 2

HCID 9864CyanamideHCID 12436302Ethanimidic acid, 2-cyano-, methyl ester, hydrochloride (1:1)

Product 1

HCID 12272861HCID 12272861, compoundYield 91.8%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

2.69 g of methyl cyanoacetimidate hydrochloride, 1.68 g of cyanamide and 5.0 g of molecular sieve (type 4A, 60 mesh through) were suspended in 30 ml of benzene and the suspension was made to react for 5 hours at 25°C under stirring. After reaction, insoluble materials were filtered off and then the filtrate was concentrated to dryness in vacuo to give 2.26 g of methyl N-cyanocyanoacetimidate (yield 91.2%) mp 45.5°C.

Workup

  1. customto react for 5 hours at 25°C
  2. customAfter reaction, insoluble materials
  3. filtrationwere filtered off
  4. concentrationthe filtrate was concentrated to dryness in vacuo

Sources & evidence

ORD record
ord-02cb4942e9414deb8c69533af79c931b
Source dataset
uspto-grants-1976_04
Patent number
US03948915

Reaction notes

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