HCID 21416630, compound → HCID 21416627, compound

HRID 1604937Notes

Reaction equation

HRID 1604937 reaction equation
ClN1[C:7]2=[C:8]([C:12]3[O:13][C:14]([N+:17]([O-:19])=[O:18])=[CH:15][CH:16]=3)[NH:9][N:10]([CH3:11])[C:6]2=CN(C)C1.ClC1[N:27]=[CH:26][N:25]=[C:24]2[N:28](C)N=C(C3OC([N+]([O-])=O)=CC=3)[C:23]=12>>[NH2:27][C:26]1[N:25]=[C:24]([CH3:23])[N:28]=[C:6]2[N:10]([CH3:11])[N:9]=[C:8]([C:12]3[O:13][C:14]([N+:17]([O-:19])=[O:18])=[CH:15][CH:16]=3)[C:7]=12

Participants

3

Reactant 2

HCID 21416630HCID 21416630, compoundHCID 86733198HCID 86733198, compound

Product 1

HCID 21416627HCID 21416627, compound

Procedure

The procedure described in Example 3b was repeated using 4-chloro-1,6-dimethyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4]pyrimidine as starting material instead of 4-chloro-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine, the reaction conditions being the same. The crystalline product was collected, washed with water and dried. Recrystallisation from dimethyl formamide gave 4-amino-1,6-dimethyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine having decomposition point > 300°C. identical with the product obtained in Example 2.

Workup

  1. customthe reaction conditions
  2. customThe crystalline product was collected
  3. washwashed with water
  4. customdried
  5. customRecrystallisation from dimethyl formamide

Sources & evidence

ORD record
ord-3247f2b6786d49cebef0595d7e0d412a
Source dataset
uspto-grants-1976_04
Patent number
US03948913

Reaction notes

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