HCID 21416630, compound → HCID 21416629, compound

HRID 1604938Notes

Reaction equation

HRID 1604938 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH2:8][CH3:9])[N:5]=[C:4]2[N:10]([CH3:21])[N:11]=[C:12]([C:13]3[O:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=3)[C:3]=12.ClC1N=C[N:26]=C2N(C)N=C(C3OC([N+]([O-])=O)=CC=3)C=12>>[NH2:26][C:2]1[N:7]=[C:6]([CH2:8][CH3:9])[N:5]=[C:4]2[N:10]([CH3:21])[N:11]=[C:12]([C:13]3[O:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=3)[C:3]=12

Participants

3

Reactant 2

HCID 21416630HCID 21416630, compoundHCID 21416647HCID 21416647, compound

Product 1

HCID 21416629HCID 21416629, compound

Procedure

The procedure described in Example 3b was repeated using 4-chloro-6-ethyl-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine as starting material instead of 4-chloro-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine, the reaction conditions being the same. The crystalline product was recrystallised from dimethyl formamide to give 4-amino-6-ethyl-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine, having decomposition point 294°C.

Workup

  1. customthe reaction conditions
  2. customThe crystalline product was recrystallised from dimethyl formamide

Sources & evidence

ORD record
ord-b5a3269880c5424aa434f8709c19e047
Source dataset
uspto-grants-1976_04
Patent number
US03948913

Reaction notes

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