HCID 21416630, compound → HCID 21416635, compound

HRID 1604939Notes

Reaction equation

HRID 1604939 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH:8]([CH3:10])[CH3:9])[N:5]=[C:4]2[N:11]([CH3:22])[N:12]=[C:13]([C:14]3[O:15][C:16]([N+:19]([O-:21])=[O:20])=[CH:17][CH:18]=3)[C:3]=12.ClC1N=C[N:27]=C2N(C)N=C(C3OC([N+]([O-])=O)=CC=3)C=12>>[NH2:27][C:2]1[N:7]=[C:6]([CH:8]([CH3:10])[CH3:9])[N:5]=[C:4]2[N:11]([CH3:22])[N:12]=[C:13]([C:14]3[O:15][C:16]([N+:19]([O-:21])=[O:20])=[CH:17][CH:18]=3)[C:3]=12

Participants

3

Reactant 2

HCID 21416630HCID 21416630, compoundHCID 21416642HCID 21416642, compound

Product 1

HCID 21416635HCID 21416635, compound

Procedure

The procedure described in Example 3b was repeated using 4-chloro-6-isopropyl-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine as starting material instead of 4-chloro-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine, the reaction conditions being the same. The crystalline product was recrystallized from dimethylformamide to give 4-amino-6-isopropyl-1-methyl-3-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidine having decomposition point 230°C.

Workup

  1. customthe reaction conditions
  2. customThe crystalline product was recrystallized from dimethylformamide

Sources & evidence

ORD record
ord-29c779bf478d40eaa9f967192ca3be4a
Source dataset
uspto-grants-1976_04
Patent number
US03948913

Reaction notes

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