HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Oxo-2,3-dihydro-1,3-thiazole-4-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Oxo-2,3-dihydro-1,3-thiazole-4-carboxylic acid | HCID 20550181 | — |
| Product | 2-Oxo-2,3-dihydro-1,3-thiazole-4-carbonyl chloride | HCID 21548231 | — |
Reaction Steps
A mixture of 29 g of 4-carboxy-4-thiazoline-2-one [Enlenmeyer et al, Helv., Chim. Acta., Vol. 27 (1944), p.1432-6] and 200 ml of thionyl chloride was refluxed for 24 hours and was then cooled. The mixture was vacuum filtered to obtain 21 g of 4-chloroformyl-4-thiazoline-2-one melting at 184°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03948925 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-12e104f2cab947bfbcd82d04910d91a4 |
| Source note | uspto-grants-1976_04 |