Water → HCID 21400655, compound

Participants

Reaction Conditions

Reaction Steps

A solution of pyrogallol (50 parts) in ethyl methyl ketone (200 parts) was stirred and heated to 50°C, then phosphorus pentoxide was added portionwise at such a rate that the temperature remained about 80°C. After stirring for a further 30 minutes at about 50°C the liquid layer was poured into cold water (1,000 parts) and the crude product isolated by extracting with benzene and evaporating the extracts. Distillation of the crude product gave pure 4-hydroxy-2-ethyl-2-methyl-1,3-benzodioxole (39.5 parts), boiling point 84°-85°C/0.4 mm., melting point 48°-50°C.

Provenance & Evidence