Bromoform → HCID 21549189, compound

HRID 1605120Notes

Reaction equation

HRID 1605120 reaction equation
[CH:1]([C:3]1[CH:17]=[CH:16][C:6]([O:7][C:8]([CH3:15])([CH3:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:5][CH:4]=1)=[CH2:2].CC(C)([O-])C.[K+].[CH:24]([Br:27])(Br)[Br:25]>>[Br:25][C:24]1([Br:27])[CH2:2][CH:1]1[C:3]1[CH:17]=[CH:16][C:6]([O:7][C:8]([CH3:15])([CH3:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 5558BromoformHCID 104107Ethyl 2-(4-vinylphenoxy)isobutyrateHCID 23665647Potassium tert-butoxide

Product 1

HCID 21549189HCID 21549189, compound

Procedure

Ethyl 2-[p-(2,2-dibromocyclopropyl)phenoxy]-2-methylpropionate was prepared from 23.4 g. of ethyl 2-(p-vinylphenoxy)-2-methylpropionate, 39.2 g. of potassium t-butoxide and 198 g. of bromoform according to the procedure described above in Example 1, part (b). The product was isolated and hydrolyzed without further purification.

Workup

  1. customThe product was isolated
  2. customhydrolyzed without further purification

Sources & evidence

ORD record
ord-3dbff45f43a64b79a896177ebca827a9
Source dataset
uspto-grants-1976_04
Patent number
US03948973

Reaction notes

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