Sodium hydrosulfide → 1,1-Dimethoxy-7-mercapto-3,7-dimethyloctane

HRID 1605130Notes

Reaction equation

HRID 1605130 reaction equation
[CH3:1][O:2][CH:3]([O:14][CH3:15])[CH2:4][CH:5]([CH3:13])[CH2:6][CH2:7][CH2:8][C:9](Cl)([CH3:11])[CH3:10].[SH-:16].[Na+]>CO>[CH3:1][O:2][CH:3]([O:14][CH3:15])[CH2:4][CH:5]([CH3:13])[CH2:6][CH2:7][CH2:8][C:9]([SH:16])([CH3:11])[CH3:10]

Participants

4

Reactant 2

HCID 28015Sodium hydrosulfideHCID 215493461,1-Dimethoxy-7-chloro-3,7-dimethyloctane

Product 1

HCID 215493991,1-Dimethoxy-7-mercapto-3,7-dimethyloctane

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 10 g. of 1,1-dimethoxy-7-chloro-3,7-dimethyloctane, 1.1 equivalents of sodium hydrosulfide and 100 ml. of methanol is refluxed for 24 hours. After cooling, solvent is evaporated under reduced pressure and the concentrate taken up in ether. The ether solution is washed with water, dried over magnesium sulfate and then evaporated to give 1,1-dimethoxy-7-mercapto-3,7-dimethyloctane.

Workup

  1. temperatureAfter cooling
  2. customsolvent is evaporated under reduced pressure
  3. washThe ether solution is washed with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

Sources & evidence

ORD record
ord-99a6b62fc3c74337838fb852eec95a0a
Source dataset
uspto-grants-1976_04
Patent number
US03948996

Reaction notes

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