反应详情

To 350 ml. of ethanol, 105 ml. of water and 70 ml. of 50% aqueous sodium hydroxide is added 46.5 g. of methyl 11-methylthio-3,7,11-trimethyldodeca-2,4-dienoate. The mixture is refluxed for about 18 hours. After cooling, alcohol is removed in vacuo. Water is added followed by acidification and then extraction with ether to yield 11-methylthio-3,7,11-trimethyldodeca-2,4-dienoic acid.

1. temperatureThe mixture is refluxed for about 18 hours
2. temperatureAfter cooling
3. customalcohol is removed in vacuo
4. additionWater is added
5. extractionextraction with ether