Chloroacetone → HCID 21549496, compound

HRID 1605151Notes

Reaction equation

HRID 1605151 reaction equation
[CH3:1][C:2]1[NH:3][CH2:4][CH2:5][N:6]=1.Cl[CH2:8][C:9](=[O:11])[CH3:10]>CC(C)=O>[O:11]=[C:9]([CH3:10])[CH2:8][N:6]1[CH2:5][CH2:4][N:3]=[C:2]1[CH3:1]

Participants

4

Reactant 2

HCID 6571ChloroacetoneHCID 107982-Methylimidazoline

Product 1

HCID 21549496HCID 21549496, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 8.4 g. of 2-methyl-2-imidazoline and 9.25 g. of chloroacetone is refluxed in 100 ml. of acetone for two hours. The solvent is removed in vacuo, and the residue is taken up in water and neutralized with 1N sodium hydroxide. Extracting with chloroform, drying and removing the solvent in vacuo gives 1-(2-oxopropyl)-2-methyl-2-imidazoline.

Workup

  1. additionA mixture of 8.4 g
  2. customThe solvent is removed in vacuo
  3. extractionExtracting with chloroform
  4. customdrying
  5. customremoving the solvent in vacuo

Sources & evidence

ORD record
ord-34d2bb8c50b0406980cf8c1cd4bdecdd
Source dataset
uspto-grants-1976_04
Patent number
US03949076

Reaction notes

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