HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1605171Generated: October 26, 2026
Hydrochloric Acid → N-(4-benzoylphenyl)acetamide
https://huagongshe.com/reaction/1605171
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetanilide | HCID 904 | — |
| Reactant | 1,1-Dichloroethane | HCID 6365 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | N-(4-benzoylphenyl)acetamide | HCID 228532 | — |
Reaction Steps
An ice-cooled solution of 5 grams of acetanilide and 15 g. of aluminum chloride in 75 ml. of dichloroethane is treated with 5 g. of benzoyl chloride in portions. The mixture is then heated at 80° C for 3 hours, decomposed with ice and dilute hydrochloric acid and the resulting solid isolated by suction filtration and recrystallized from ethanol:water to give p-benzoylacetanilide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03949084 |
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| Source dataset | uspto-grants-1976_04 |
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| ORD ID | ord-7671b3111bdd4df8ac7ebec234f49312 |
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| Source note | uspto-grants-1976_04 |
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