4-Methylbenzylamine → HCID 86733218, compound

Participants

Reaction Steps

A solution of N,N',S-trimethylisothiourea hydriodide, m.p. 208° -212° (9.84 g.) and p-methyl-benzylamine (4.84 g.) in ethanol (10 ml.) was refluxed for 31/2 hours, filtered, and refluxed for a further 21/2 hours. The solution was then concentrated, and the solid that separated was collected and crystallised from methanol-ethanol to give N-p-methylbenzyl-N', N"-dimethyl-guanidine hydriodide, m.p. 204° - 207°. Recrystallised from water, the m.p. rose to 209° - 212°.

Provenance & Evidence