Sodium Carbonate → HCID 12228986, compound

Participants

Reaction Steps

A stirred suspension of 13.50 g. (0.06 mole) of (4-chloro-6-propyl-2-pyrimidinylthio)acetonitrile, 9.00 g. (0.06 mole) of piperonylamine and 6.36 g. (0.06 mole) of sodium carbonate was heated under reflux for six hours. The mixture was filtered and the filtrate was evaporated in a rotary evaporator. The residue was dissolved in ethyl acetate, diluted with petroleum ether and was cooled in ice. The precipitate which formed was collected and recrystallized from a mixture of ethanol-petroleum ether to give 3.0 g. of product, m.p. 92°-94°.

Provenance & Evidence