HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13290642, compound → 5-Benzyl-4-hydroxymethyloxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13290642 | HCID 13290642 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Benzyl-4-hydroxymethyloxazole | HCID 20557606 | — |
Reaction Steps
Methyl 5-benzyl-4-oxazolecarboxylate is reduced with lithium aluminum hydride in tetrahydrofuran to give 5-benzyl-4-hydroxymethyloxazole, which on reaction with thionyl chloride is converted to 5-benzyl-4-chloromethyloxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03950353 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-27f16a9dd284474e821808eeb3f170d9 |
| Source note | uspto-grants-1976_04 |