O-Phenylenediamine → Thiophamine

Participants

Reaction Steps

11.7 Parts of methoxycarbonylisothiocyanate is dissolved in 50 parts of benzene and is added to a suspension of 10.8 parts of o-phenylenediamine suspended in 200 parts of benzene at 10°-15°C. The mixture is stirred for 1 hour at room temperature and the product is then removed by filtration yielding 13.7 parts of methyl 4-(o-aminophenyl)-3-thioallophanate, m.p. 182°-183° (D). The melting point is raised to 186°-187° (D) after recrystallization from acetonitrile.

Provenance & Evidence