Hydrochloric Acid → HCID 178507797, compound

Participants

Reaction Steps

5-Amino-3-mercapto-4-phenylthiobenzoic acid (1.6 g) is dissolved in 1 N sodium hydrogen carbonate (50 ml), and after addition of benzyl bromide (0.7 ml), the reaction mixture is stirred for 20 hours. The resulting suspension of the sodium salt of the reaction product is adjusted to pH 2 by addition of 4 N hydrochloric acid. The precipitated 5-amino-3-benzylthio-4-phenylthiobenzoic acid is collected by filtration and recrystallized from aqueous ethanol to yield the compound with a melting point of 170.5°-172° C.

Provenance & Evidence