4-Phenoxy-5-sulfamyl-3-(3-thienylmethylthio)benzoic acid → HCID 21520106, compound

HRID 1605526Notes

Reaction equation

HRID 1605526 reaction equation
[O:1]([C:8]1[C:16]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]=1[S:21][CH2:22][C:23]1[CH:27]=[CH:26][S:25][CH:24]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:28](SC1C=C(C=C(S(=O)(=O)N)C=1OC1C=CC=CC=1)C(O)=O)CCC>>[O:1]([C:8]1[C:16]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:15][C:11]([C:12]([O:14][CH3:28])=[O:13])=[CH:10][C:9]=1[S:21][CH2:22][C:23]1[CH:27]=[CH:26][S:25][CH:24]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 215200814-Phenoxy-5-sulfamyl-3-(3-thienylmethylthio)benzoic acidHCID 54574929HCID 54574929, compound

Product 1

HCID 21520106HCID 21520106, compound

Procedure

By replacing in Example 47 4-phenoxy-5-sulfamyl-3-(3-thienylmethylthio)benzoic acid for 3-n-butylthio-4-phenoxy-5-sulfamylbenzoic acid and following the procedure described, methyl 4-phenoxy-5-sulfamyl-3-(3-thienylmethylthio)benzoate is obtained with a melting point of 148°-149° C.

Sources & evidence

ORD record
ord-f4fdf99080b440fb81a0095fdcbba214
Source dataset
uspto-grants-1976_04
Patent number
US03950376

Reaction notes

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