3-Benzyloxy-5-nitro-4-phenylbenzoic acid → HCID 21546871, compound

HRID 1605553Notes

Reaction equation

HRID 1605553 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([N+:24]([O-])=O)[C:17]=1[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]([OH:14])=[O:13])[C:2]1C=CC=C[CH:3]=1.[N+](C1C(C2C=CC=CC=2)=C(OCCC)C=C(C=1)C(O)=O)([O-])=O>>[NH2:24][C:16]1[C:17]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:9]([O:8][CH2:1][CH2:2][CH3:3])[CH:10]=[C:11]([CH:15]=1)[C:12]([OH:14])=[O:13]

Participants

3

Reactant 2

HCID 215468443-Benzyloxy-5-nitro-4-phenylbenzoic acidHCID 21546873HCID 21546873, compound

Product 1

HCID 21546871HCID 21546871, compound

Procedure

By replacing in Example 2, step D, 3-benzyloxy-5-nitro-4-phenylbenzoic acid with 5-nitro-4-phenyl-3-n-propoxybenzoic acid, and following the procedure described, 5-amino-4-phenyl-3-n-propoxybenzoic acid is obtained with a melting point of 101°-102° C.

Sources & evidence

ORD record
ord-eeac891f9b22481bb2d770db2cf9d863
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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